科学家完成全部癌症基因组的全面研究
文章来源:未知 文章作者:enread 发布时间:2020-02-11 01:35 字体: [ ] 
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By completing the most comprehensive study of whole cancer genomes to date, an international team of scientists has 1 deeper understanding of cancer, paving the way for more effective treatment, the Wellcome Sanger Institute said on Wednesday.
 
威康桑格学院周三表示,迄今全部癌症基因组的综合研究已完成,来自世界各地的科学家对癌症的研究更加深入,为更有效的治疗铺平了道路。
 
The ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Project (PCAWG), or the Pan-Cancer Project, is a 2 involving more than 1,300 scientists and clinicians from 37 countries. Researchers from the Wellcome Sanger Institute in the UK are part of the team.
 
They analysed more than 2,600 genomes of 38 different 3 types, creating a huge resource of primary cancer genomes. This was then the launch-point for 16 working groups studying multiple aspects of cancer's development, causation, progression and classification.
 
In a series of papers published Wednesday in the journal Nature and its 4 journals, the Pan-Cancer Project discovers causes of 5 unexplained cancers, 6 cancer-causing events and zeroes in on 7 of development.
 
"The genome of each patient's cancer is unique, but there are a finite set of 8 patterns, so with large enough studies we can identify all these patterns to 9 10 and treatment," said Dr. Peter Campbell, member of the Pan-Cancer Project 11 committee and head of Cancer, Ageing and Somatic 12 at the Wellcome Sanger Institute.
 
Tumour types can be identified 13 according to the patterns of 14 changes seen throughout the genome, potentially aiding the diagnosis of a patient's cancer where conventional clinical tests could not identify its type, and knowledge of the exact tumour type could also help tailor treatments, according to the Wellcome Sanger Institute.


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1 60d1f073f04681f98098b8374f4a7693     
v.收集并(通常)贮藏(某物),取得,获得( garner的过去式和过去分词 )
参考例句:
  • Mr. Smith gradually garnered a national reputation as a financial expert. 史密斯先生逐渐赢得全国金融专家的声誉。 来自《简明英汉词典》
  • He has garnered extensive support for his proposals. 他的提议得到了广泛的支持。 来自辞典例句
2 bW7yD     
n.合作,协作;勾结
参考例句:
  • The two companies are working in close collaboration each other.这两家公司密切合作。
  • He was shot for collaboration with the enemy.他因通敌而被枪毙了。
3 tumour     
n.(tumor)(肿)瘤,肿块
参考例句:
  • The surgeons operated on her for a tumour.外科医生为她施行了肿瘤切除手术。
  • The tumour constricts the nerves.肿瘤压迫神经。
4 78057fb733c9c93ffbdc5f0ed15ef458     
adj. 附属的, 有关连的
参考例句:
  • The hospital is affiliated with the local university. 这家医院附属于当地大学。
  • All affiliated members can vote. 所有隶属成员都有投票权。
5 bkzzzC     
adv.以前,先前(地)
参考例句:
  • The bicycle tyre blew out at a previously damaged point.自行车胎在以前损坏过的地方又爆开了。
  • Let me digress for a moment and explain what had happened previously.让我岔开一会儿,解释原先发生了什么。
6 42a4e5e5fdaaa77bfc7085fcb54b536a     
准确地找出或描述( pinpoint的第三人称单数 ); 为…准确定位
参考例句:
  • The bombs hit the pinpoints at which they were aimed. 炸弹精确地击中了目标。
  • There's really no point in arguing about pinpoints. 为芝麻绿豆般的小事争论实在毫无意义。
7 d0db71d70348ef1c49f05f59097917b8     
n.机械( mechanism的名词复数 );机械装置;[生物学] 机制;机械作用
参考例句:
  • The research will provide direct insight into molecular mechanisms. 这项研究将使人能够直接地了解分子的机理。 来自《简明英汉词典》
  • He explained how the two mechanisms worked. 他解释这两台机械装置是如何工作的。 来自《简明英汉词典》
8 8kLzK8     
adj.往复的,再次发生的
参考例句:
  • This kind of problem is recurring often. 这类问题经常发生。
  • For our own country, it has been a time for recurring trial. 就我们国家而言,它经过了一个反复考验的时期。
9 WIoxY     
v.使优化 [=optimise]
参考例句:
  • We should optimize the composition of the Standing Committees.优化人大常委会组成人员的结构。
  • We should optimize our import mix and focus on bringing in advanced technology and key equipment.优化进口结构,着重引进先进技术和关键设备。
10 GvPxC     
n.诊断,诊断结果,调查分析,判断
参考例句:
  • His symptoms gave no obvious pointer to a possible diagnosis.他的症状无法作出明确的诊断。
  • The engineer made a complete diagnosis of the bridge's collapse.工程师对桥的倒塌做一次彻底的调查分析。
11 3hRzbi     
n.操舵装置
参考例句:
  • He beat his hands on the steering wheel in frustration. 他沮丧地用手打了几下方向盘。
  • Steering according to the wind, he also framed his words more amicably. 他真会看风使舵,口吻也马上变得温和了。
12 t1PyM     
n.变化,变异,转变
参考例句:
  • People who have this mutation need less sleep than others.有这种突变的人需要的睡眠比其他人少。
  • So far the discussion has centered entirely around mutation in the strict sense.到目前为止,严格来讲,讨论完全集中于围绕突变问题上。
13 oJHyf     
adv.准确地,精确地
参考例句:
  • It is hard to hit the ball accurately.准确地击中球很难。
  • Now scientists can forecast the weather accurately.现在科学家们能准确地预报天气。
14 PgIxp     
adj.遗传的,遗传学的
参考例句:
  • It's very difficult to treat genetic diseases.遗传性疾病治疗起来很困难。
  • Each daughter cell can receive a full complement of the genetic information.每个子细胞可以收到遗传信息的一个完全补偿物。
TAG标签: cancer treatment genomes
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